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Enome. Thus, VLP-based vaccines offer a safer and more appealing alternativeEnome. Thus, VLP-based vaccines offer a safer and more appealing alternative to live, attenuated and inactivated vaccination strategies. Intrinsic characteristics of VLP - such as the particulate nature and the size, the highly ordered and repetitive structure, the charge surface - coupled with immunogenic properties
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Their growth ad matrix crack population). Raine's syndrome, a rare condition with an incidence of 1/1,000,000, is due to a mutation in FAM20C the Golgi protein kinase that phosphorylates most secreted phosphoproteins including SIBLING proteins [160,161]. The osteosclerosis characteristic of this skeletal dysplasia provides clinical support for the importance of controlled phosphorylation of IDPs f
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R calcium ions or hydroxyapatite was verified by circular dichroism, small angle scattering and vibrational spectroscopy (Figure 4). Based on modeling, the phosphorylated peptide folded differently when associated with a model of type I collagen than did the non-phosphorylated peptide (Figure 5). These changes in conformation associated with post-translational modifications, could facilitate nucle
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DSPP in bone, redundant functions of the protein or differences in the processing of DSPP in bone and dentin [121, 139]. It should be noted that immature Dspp KO mice, contrasted with patients with DSPP mutations, have hypomineralized bones [89]. It is not known whether this is corrected as the mice age. In vitro TEM data suggested that DSPP could induce highly oriented intrafibrillar HA mineraliz
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DSPP in bone, redundant functions of the protein or differences in the processing of DSPP in bone and dentin [121, 139]. It should be noted that immature Dspp KO mice, contrasted with patients with DSPP mutations, have hypomineralized bones [89]. It is not known whether this is corrected as the mice age. In vitro TEM data suggested that DSPP could induce highly oriented intrafibrillar HA mineraliz
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On by age, race, gender, grade, resection status, the TNM variables lymph node status (N0; No regional lymph node metastasis, N1; Regional lymph node metastasis, and NX;Quadri et al. BMC Cancer (2017) 17:Page 3 ofRegional lymph nodes cannot be assessed) and distant metastasis (M0; No distant metastasis, and M1; Distant metastasis), SEER stage (localized, regional, and distant), radiation, and prim
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On by age, race, gender, grade, resection status, the TNM variables lymph node status (N0; No regional lymph node metastasis, N1; Regional lymph node metastasis, and NX;Quadri et al. BMC Cancer (2017) 17:Page 3 ofRegional lymph nodes cannot be assessed) and distant metastasis (M0; No distant metastasis, and M1; Distant metastasis), SEER stage (localized, regional, and distant), radiation, and prim
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Te) (PACA) and poly(methyl methacrylate) (PMMA) nanoparticles - solid lipidTe) (PACA) and poly(methyl methacrylate) (PMMA) nanoparticles - solid lipid nanoparticles (SLNs), liposomal delivery systems, virosomes, immune stimulating complexes (ISCOMs), virus-like particles (VLPs), non-degradable nanoparticles, colloidal ironbased preparations and many others, while emulsions include heterogeno